Specific detection of Treponema pallidum in clinical samples: validation of a qPCR assay combining two genomic targets. (2022) Salle R, Mayslich C, Grange PA, Leducq V, Ollagnier G, Heller U, Saule J, Martinet P, Robert JL, Benhaddou N, Fouéré S, Dupin N. Sex Transm Infect. In press

Syphilis is a rare cause of erythema nodosum: a case report. (2022) Anthony N, Duquenne S, Zemali N, Foucher A, Dupin N, Bertolotti A. Infect Drug Resist. 15:307-310.

2020 European guideline on the management of syphilis. (2021) Janier M, Unemo M, Dupin N, Tiplica GS, Potocnik M, Patel R. J Eur Acad Dermatol Venereol. 35(3):574-588

Syphilis : une infection toujours d’actualité. (2021) Benhaddou N, Grange P, Dupin N. Revue Française des Laboratoires. N° 530.

High prevalence of syphilis in women, minors and precarious patients: a cross-sectional study in a Reunion Island sexually transmitted infection clinic, 2017-2020. (2021) Delfosse A, Bouscaren N, Dupin N, Jaubert J, Tran PL, Saint Pastou C, Manaquin R, Poubeau P, Gerardin P, Bertolotti A. J Eur Acad Dermatol Venereol. 35(11):2287-2292.

Ceftriaxone compared with benzylpenicillin in the treatment of neurosyphilis in France: a retrospective multicentre study. (2021) Bettuzzi T, Jourdes A, Robineau O, Alcaraz I, Manda V, Molina JM, Mehlen M, Cazanave C, Tattevin P, Mensi S, Terrier B, Régent A, Ghosn J, Charlier C, Martin-Blondel G, Dupin N. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30857-4.

Azithromycin resistance in Treponema pallidum in Reunion island: a cross-sectional study. (2021) Bourgeois G, Grange P, Saint-Pastou Terrier C, Koumar Y, Manaquin R, Zemali N, Poubeau P, Dupin N, Jaubert J, Bertolotti A. Ann Dermatol Venereol. 16:S0151-9638(21)00015-6.

European guideline on the management of syphilis. (2020) Janier M, Unemo M, Dupin N, Tiplica GS, Potočnik M, Patel R. J Eur Acad Dermatol Venereol. doi: 10.1111/jdv.16946.

Serological diagnosis of secondary syphilis in a Rituximab-treated patient: an emerging diagnosis challenge. (2020) Lefeuvre C, Croué A, Abgueguen P, Letzelter M, Ducancelle A, Grange P, Benhaddou N, Dupin N, Le Guillou-Guillemette H, Le Clec'h C. J Eur Acad Dermatol Venereol. doi:10.1111/jdv.17126.

Surveillance of antibiotic resistance genes in Treponema pallidum subspecies pallidum from patients with early syphilis in France.(2020) Sanchez A, Mayslish C, Malet I, Grange PA, Janier M, Saule J, Martinet P, Robert JL, Moulene D, Truchetet F, Pinault AL, Vermersch-Langlin A, Benhaddou N, Chanal J, Dupin N. Acta Dermatol Venereol. 100(14):adv00221.

Oral forms of secondary syphilis, an illustration of the pitfalls set by the great imitator. (2020) Lampros A, Seta V, Gerhardt P, Isnard C, Husson C, Dupin N. J Am Acad Dermatol. 2020 Apr 24:S0190-9622(20)30705-2.

Use of a multiplex assay to assess the presence of Treponema pallidum in mucocutaneous ulcerations in patients with suspected syphilis. (2020) Grange PA, Jary A, Isnard C, Burrel S, Boutolleau D, Touati A, Bébéar C, Saule J, Martinet P, Robert JL, Moulene D, Vermersch-Langlin A, Benhaddou N, Janier M, Dupin N. J Clin Microbiol. 59(2):e01994-20.

Bacterial Sexually Transmitted Infections in France: Recent Trends and Patients' Characteristics in 2016. (2019) Ndeikoundam Ngangro N, Viriot D, Fournet N, Pioche C, De Barbeyrac B, Goubard A, Dupin N, Berçot B, Fouéré S, Alcaraz I, Ohayon M, Spenatto N, Vernay-Vaisse C, Pillonel J, Lot F; Referents for the regional offices of the French national public health agency.  Euro Surveill.24(5):1800038.

HIV and other STI on the grill. (2019) Dupin N. Ann Dermatol Venereol. 2019 146(12S):A3-A4.

Syphilis Congénitale. (2019) Benhaddou N. Revue Francophone des laboratoires

Congenital syphilis: A prospective study of 22 cases diagnosed by PCR. (2019) Garel B, Grange P, Benhaddou N, Schaub B, Desbois-Nogard N, Thouvenin M, Lepoutre X, Levy R, Navarro C, Charlier C, Ndeikoundam Ngangro N, Viriot D, Dupin N. Ann Dermatol Venereol.2019 Nov;146(11):696-703.

Directly sequenced genomes of contemporary strains of syphilis reveal recombination-driven diversity in genes encoding predicted surface-exposed antigens. (2019) Grillová L, Oppelt J, Mikalová L, Nováková M, Giacani L, Niesnerová A, Noda AA, Mechaly AE, Pospíšilová P, Čejková D, Grange PA, Dupin N, Strnadel R, Chen M, Denham I, Arora N, Picardeau M, Weston C, Forsyth RA, Šmajs D. Front Microbiol. 10:1691.

Une syphilis «précoce». (2019) Sanchez A, Del Giudice P, Peneau A, Grange P, Dupin N, Hubiche T. Ann Dermatol Venereol.https://doi.org/10.1016/j.annder.2019.10.032

Treatment of syphilis associated cerebral vasculitis: Reappearance of an old question. (2018) Nageau A, Rodriguez-Régent C, Dion J, Dupin N, Mouthon L, Le Jeunne C, Régent A. Am J Med. 131(12):1516-1519.

Relevance of healthcare reimbursement data to monitor syphilis epidemic: an alternative surveillance through the national health insurance database in France, 2011-2013. (2018) Ngangro Ndeikoundam N, Viriot D, Lucas E, Boussac-Zarebska M, Lot F, Dupin N, La Ruche G. BMJ Open. 8(7):e020336.

Multi-locus sequence typing of Treponema pallidum subsp. pallidum present in clinical samples from France: Infecting treponemes are genetically diverse and belong to 18 allelic profiles. (2018) Pospíšilová P, Grange PA, Grillová L, Mikalová L, Martinet P, Janier M, Vermersch A, Benhaddou N, Del Giudice P, Alcaraz I, Truchetet F, Dupin N, Šmajs D. PLoS ONE. 13(7):e0201068.

Treatment of syphilis-associated cerebral vasculitis: reappearance of an old question. (2018) Mageau A, Rodriguez-Régent C, Dion J,Dupin N, Mouthon L, Le Jeunne C, Régent A. Am J Med. 131(12):1516-1519.

Human Treponema pallidum 11q/j isolate belongs to subsp. endemicum but contains two loci with a sequence in TP0548 and TP0488 similar to subsp. pertenue and subsp. pallidum, respectively. (2017) Mikalova L, Strouhal M, Oppelt J, Grange PA, Janier M, Benhaddou N, Dupin N, Smajs D. PloS Negl Trop Dis. 11(3):e0005434.

Prognostic factors in syphilis uveitis. (2017) Hoogewoud F, Frumholtz L, Loubet P, Charlier C, MD, Blanche P, Lebeaux D, Benhaddou N,Sedira N, Coutte L, Vanhaecke C, Launay O, Le Jeunne C, Héron E, Monnet D, Lortholary O, Sahel JA, Dupin N, Brézin A, Errera MH, Salah S, Groh M.  Ophtalmol. 124:1808-1816.

Immune reconstitution inflammatory syndrome presenting as secondary syphilis with polymorphous erythema and knee arthritis.(2017) Brochard J, Khatchatourian L, Woaye-Hune P, Biron C, Lefebvre M, Denis-Musquer M, Grange P, Dupin N, Raffi F. J Eur Acad Dermatol Venereol. 31 :e381-e382.

Tréponèmes pathogènes pour l’homme. (2017) Dupin N, Grange P. n°92, ESKA

Bulletin de veille sanitaire thématique IST & VIH Réunion & Mayotte: Point sur la syphilis congénitale. (2017) Benhaddou N, Grange P, Dupin N. BVS 35:19-22.

Isolation of Treponema DNA from necrophagous flies in a natural ecosystem. (2016) Knauf S, Raphael J, Mitjà O, Lejora IA, Chuma IS, Batamuzi EK, Keyyu JD, Fyumagwa R, Lüert S, Godornes C, Liu H, Schwarz C, Šmajs D, Grange P, Zinner D, Roos C, Lukehart SA. EBioMedecine. 16:30343-30347.

Treponema pallidum 11qj subtype may correspond to a Treponema pallidum subsp. endemicum strain. (2016) Grange P, Mikalova L, Gaudin C, Strouhal M, Janier M, Benhaddou N, Smajs D, Dupin N. Sex Trans Dis. 43:517-518. 

Clinical and biological characteristics of neurosyphilis in 40 patients, and evaluation of Treponema pallidum nPCR on the CSF.(2016) Vanhaecke C, Grange P, Benhaddou N, Blanche P, Salmon D, Parize P, Lortholary O, Caumes E, Pelloux I, Epaulard O, Guinard J, Dupin N, and the Neurosyphilis network. Clin Infect Dis. 63:1180-1186.

Pulmonary Consolidations Due to Secondary Syphilis with Positive Bronchial Washing Immunohistochemistry. (2016) Jeny F, Fargelat A, Laurent-Roussel S, Nault JC, Dupin N, Grange P, Nunes H, Valeyre D. Am J Respir Crit Care Med. 193:1061-1061.

Periostitis in secondary syphilis with prozone phenomenon. (2016) Mahévas T, Chanal J, Franck N, Laurent S, Avril MF, Dupin N. Rheumatology (Oxford). 55:1931.

Syphilis and pregnancy. (2015) Charlier C, Benhaddou N, Dupin N. Presse Med. 44:631-8.

Clinical Aspects of Syphilis Reinfection in HIV-Infected Patients. (2015) Courjon J, Hubiche T, Dupin N, Grange PA, Del Giudice P. Dermatology. 230:302-7.

2014 European guideline on the management of syphilis. (2014) Janier M, Hegyi V, Dupin N, Unemo M, Tiplica GS, Potočnik M, French P, Patel R. J Eur Acad Dermatol Venereol. 28:1581-1593.

Molecular subtyping of Treponema pallidum in Paris, France. (2013) Grange PA, Allix-Beguec C, Chanal J, Benhaddou N, Gerhardt P, Morini JP, Deleuze J, Lassau F, Janier M, Dupin N.  Sex Trans Dis. 40:641-644.

Recurrent tamponade and aortic dissection in syphilis. (2013) Stansal A, Mirault T, Rossi A, Dupin N, Bruneval P, Bel A, Azarine A, Minozzi C, Deman AL, Messas E. Ann Thorac Surg. 96 :111-113.

Evaluation of a PCR Test for Detection of Treponema pallidum in Swabs and Blood. (2012) Grange PA, L. Gressier, PL Dion, D Farhi, N Benhaddou, P Gerhardt, JP Morini, J Deleuze, C Pantoja, A Bianchi, F Lassau, MF Avril, M Janier, N Dupin. J Clin Microbiol. 50:546-552.

Treponema pallidum induces systemic TH17 and TH1 cytokine responses. (2012) Bernardeschi C, Grange PA, Janier M, Gressier L, Dion PL, Benhaddou N, Bianchi A, Lassau F, Avril MF, Batteux F, Dupin N. Eur J Dermatol. 22:797-798.

Oxidative stress markers are increased since early stages of infection in syphilitic patients. (2012) Hébert-Schuster M, Borderie D, Grange PA, Lemarechal H, Kavian-Tessler N, Batteux F, Dupin N. Arch Dermatol Res. 304:689-697.